ʻO Hydroxypropyl Methyl Cellulose (HPMC), i ʻike ʻia e ka inoa kālepa hypromellose, he polymer synthetic i loaʻa mai ka cellulose kūlohelohe. ʻO ke kumu mua o ka cellulose no ka hana ʻana i ka HPMC ʻo ia ka pulp lāʻau a i ʻole ka pulupulu. ʻO ke kaʻina hana e pili ana i ka hoʻololi kemika i ka cellulose ma o ka etherification, e hoʻokomo ana i nā hui hydroxypropyl a me methyl ma luna o ka iwi kuamoʻo cellulose.

ʻO ka hana ʻana o HPMC e pili ana i kekahi mau pae:

1. ʻO ka unuhi ʻana o ka cellulose:
   • Loaʻa ka cellulose mai nā kumu mea kanu, ʻo ka pulp lāʻau a i ʻole ka pulupulu. Lawe ʻia ka cellulose a hoʻomaʻemaʻe ʻia e hana i ka pulp cellulose.
2. Alkalization:
   • Hoʻohana ʻia ka pulp cellulose me kahi solution alkaline, maʻamau ka sodium hydroxide (NaOH), e hoʻāla i nā pūʻulu hydroxyl ma ke kaulahao cellulose.
3. Etherification:
   • ʻO ka Etherification ka hana nui i ka hana ʻana o HPMC. Hoʻopili ʻia ka cellulose alkalized me ka propylene oxide (no nā pūʻulu hydroxypropyl) a me ka methyl chloride (no nā pūʻulu methyl) e hoʻokomo i kēia mau pūʻulu etera i ka iwi kuamoʻo cellulose.
4. Neutralization a me ka holoi ʻana:
   • ʻO ka hopena o ka cellulose i hoʻololi ʻia, ʻo ia hoʻi ʻo Hydroxypropyl Methyl Cellulose i kēia manawa, e hana i kahi kaʻina neutralization e wehe i nā alkali i koe. A laila holoi pono ia e hoʻopau i nā haumia a me nā huahana.
5. Hoʻomaloʻo a me ka Milling:
   • Hoʻomaloʻo ʻia ka cellulose i hoʻololi ʻia no ka wehe ʻana i ka makū a laila wili ʻia i loko o kahi pauka maikaʻi. Hiki ke hoʻomalu ʻia ka nui o ka ʻāpana ma muli o ka noi i manaʻo ʻia.

ʻO ka huahana HPMC he pauka keʻokeʻo keʻokeʻo a keʻokeʻo paha me nā pae like ʻole o ka hydroxypropyl a me ka methyl substitution. ʻO nā waiwai kikoʻī o HPMC, e like me kona solubility, viscosity, a me nā ʻano hana ʻē aʻe, e hilinaʻi ʻia ma ke ʻano o ka hoʻololi ʻana a me ke kaʻina hana.

He mea nui ia e hoʻomaopopo he semi-synthetic polymer ʻo HPMC, a ʻoiai ua loaʻa ia mai ka cellulose maoli, ua hoʻololi ʻia ke kemika nui i ka wā o ka hana hana e hoʻokō i kāna mau waiwai i makemake ʻia no nā noi ʻoihana like ʻole.