Mea hoʻonui lāʻau lapaʻau

Mea hoʻonui lāʻau lapaʻau

ʻO ka Hydroxypropyl methylcellulose (HPMC) keʻokeʻo a i ʻole ka waiu keʻokeʻo, ʻaʻohe ʻono, ʻono ʻole, pauka fibrous a granule paha, ʻaʻole i ʻoi aku ke kaumaha o ke kaumaha ma ka maloʻo ʻana ma mua o 10%, hiki ke hoʻoheheʻe ʻia i ka wai anuanu akā ʻaʻole ka wai wela, lohi i ka wai wela ʻO ka pehu, peptization, a me ka hoʻokumu ʻana i kahi ʻO ka solution colloidal viscous, ka mea i lilo i mea hoʻonā i ka wā i hoʻoluʻu ʻia, a lilo i gel ke hoʻomehana ʻia. ʻAʻole hiki ke hoʻoheheʻe ʻia ka HPMC i ka ethanol, chloroform a me ka etera. Hiki ke hoʻoheheʻe ʻia me ka methanol a me ka methyl chloride. Hiki ke hoʻoheheʻe ʻia i loko o kahi mea hoʻoheheʻe hui ʻia o ka acetone, methyl chloride a me isopropanol a me kekahi mau mea hoʻoheheʻe kūlohelohe. Hiki i kona wai wai ke ʻae i ka paʻakai (ʻaʻole i luku ʻia kāna solution colloidal e ka paʻakai), a ʻo ka pH o 1% aqueous solution he 6-8. ʻO ke ʻano mole mole o HPMC ʻo C8H15O8-(C10H18O6) -C815O, a ʻo ka nui o ka molekala pili ma kahi o 86,000.

Lapaʻau-Excipient

Loaʻa i ka HPMC ka hoʻoheheʻe wai maikaʻi i ka wai anuanu. Hiki ke hoʻoheheʻe ʻia i loko o kahi hoʻonā akaka me ka hoʻoulu ʻana i ka wai anuanu. Ma ka ʻokoʻa, ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai wela ma luna o 60 ℃ a hiki ke pehu wale. He etera cellulose non-ionic. ʻAʻohe o ka hoʻonā ionic charge, ʻaʻole pili pū me nā paʻakai metala a i ʻole nā ​​mea hoʻohui ionic organik, a ʻaʻole hoʻi me nā mea maka ʻē aʻe i ka wā o ka hoʻomākaukau ʻana; he mau waiwai anti-allergic ikaika, a me ka piʻi ʻana o ke kiʻekiʻe o ka hoʻololi ʻana i ka molecular structure, ʻoi aku kona kūpaʻa i nā allergies a ʻoi aku ka paʻa; ʻo ia hoʻi ka metabolically inert. Ma ke ʻano he mea hoʻohana lāʻau lapaʻau, ʻaʻole ia e metabolized a hoʻopaʻa ʻia. No laila, ʻaʻole ia e hāʻawi i nā calorie i nā lāʻau lapaʻau a me nā meaʻai. He haʻahaʻa ka calorie, paʻakai ʻole, a paʻakai ʻole no ka poʻe maʻi maʻi maʻi. Loaʻa i nā lāʻau allergenic a me nā meaʻai ke hoʻohana kūʻokoʻa; he paʻa paʻa i nā waikawa a me nā alkalis, akā inā ʻoi aku ka nui o ka PH ma mua o 2 ~ 11 a pili i nā mahana kiʻekiʻe a i ʻole ka lōʻihi o ka mālama ʻana, e emi ana kona viscosity; hiki i kāna mea hoʻoheheʻe wai ke hāʻawi i ka hana Surface, e hōʻike ana i ka haʻahaʻa haʻahaʻa o ka ʻili a me ka haʻahaʻa interfacial; loaʻa iā ia ka emulsification maikaʻi i ka ʻōnaehana ʻelua-phase, hiki ke hoʻohana ʻia e like me ka stabilizer kūpono a me ka colloid pale; ʻO kāna mea hoʻoheheʻe wai he mau waiwai hana kiʻiʻoniʻoni maikaʻi loa, he papa a me ka pila He mea uhi maikaʻi. ʻO ka uhi kiʻiʻoniʻoni i hana ʻia e ia nā mea maikaʻi o ka kala ʻole a me ka paʻakikī. ʻO ka hoʻohui ʻana i ka glycerin hiki ke hoʻomaikaʻi i kona plasticity.

Hiki ke hoʻomaikaʻi ʻia nā huahana QualiCell HPMC e nā waiwai aʻe ma Pharmaceutical Excipient:
· Ke hoʻoheheʻe ʻia i ka wai a hoʻoheheʻe ʻia ma o ka solvent, hana ʻo HPMC i ke kiʻi ʻoniʻoni me ka ikaika tensile kiʻekiʻe.
· Hoʻonui i ka mana paʻa .
·Hydrophilic matrix i hoʻohana pū ʻia me HPMC hydrates e hana i kahi papa gel, kaohi ʻana i ke ʻano hoʻokuʻu lāʻau.

Manaʻo Papa: Noi iā TDS
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