ʻO ka Hydroxypropyl methylcellulose (HPMC) he polymer maʻamau a hoʻohana nui ʻia i nā ʻoihana like ʻole, i ʻike ʻia no kāna mau waiwai a me nā noi.ʻO kēia pūhui he mea ia o ka cellulose, he polymer maoli i loaʻa i loko o nā paia o nā mea kanu.No ka hoʻomaopopo ʻana i ke ʻano o ka hydroxypropylmethylcellulose, pono ia e ʻimi i ke ʻano a me ka synthesis o kēia derivative cellulose.
ʻO ke ʻano o ka cellulose:
ʻO ka Cellulose kahi waiʻaʻa paʻakikī i loaʻa i kahi kaulahao laina o nā ʻāpana β-D-glucose i hoʻopili ʻia e nā paʻa β-1,4-glycosidic.Hoʻopaʻa ʻia kēia mau kaulahao glucose e nā paʻa hydrogen e hana i kahi ʻano laina laina paʻa.ʻO ka Cellulose ka mea nui i kūkulu ʻia o nā paia o nā mea kanu, e hāʻawi ana i ka ikaika a me ka paʻakikī i nā mea kanu.
Nā mea i loaʻa i ka Hydroxypropyl Methylcellulose:
Hoʻopili ʻia ka Hydroxypropyl methylcellulose e ka hoʻololi kemika cellulose a hoʻokomo i nā pūʻulu hydroxypropyl a me methyl i loko o ke kaulahao nui o cellulose.Hoʻokomo pinepine ʻia nā hana i lalo:
Pane hoʻoheheʻe:
Methylation: Ka mālama ʻana i ka cellulose me kahi solution alkaline a me ka methyl chloride e hoʻokomo i nā hui methyl (-CH3) i loko o nā hui hydroxyl (-OH) o ka cellulose.
Hydroxypropylation: Hoʻopili hou ka methylated cellulose me ka propylene oxide e hoʻokomo i nā hui hydroxypropyl (-CH2CHOHCH3) i loko o ka hale cellulose.Hoʻonui kēia kaʻina hana i ka wai a hoʻololi i nā waiwai kino o cellulose.
hoʻomaʻemaʻe:
Hoʻomaʻemaʻe ʻia ka cellulose i hoʻololi ʻia no ka wehe ʻana i nā reagents unreacted, nā huahana a i ʻole nā mea haumia.
Ka maloʻo a me ka wili ʻana:
Hoʻomaloʻo ʻia ka hydroxypropyl methylcellulose i hoʻomaʻemaʻe ʻia i loko o kahi pauka maikaʻi i mākaukau no ka hoʻohana ʻana i nā ʻano hana like ʻole.
ʻO nā mea waiwai o Hydroxypropyl Methylcellulose:
Hōʻike ʻia ke ʻano o ka hydroxypropyl methylcellulose e ka degere o ka hoʻololi ʻana, e pili ana i ke ʻano o ka hydroxypropyl a me nā hui methyl e hoʻololi i nā pūʻulu hydroxyl i ke kaulahao cellulose.Loaʻa i nā māka like ʻole o ka HPMC nā degere like ʻole o ka hoʻololi ʻana, e pili ana i ko lākou solubility, viscosity a me nā waiwai ʻē aʻe.
Hiki ke hōʻike ʻia ke ʻano kemika o ka hydroxypropyl methylcellulose (C6H7O2(OH)3-mn(OCH3)m(OCH2CH(OH)CH3)n)_x, kahi m a me n e hōʻike ana i ke degere o ka pani.
m: degere o ka methylation (nā pūʻulu methyl no ka ʻāpana glucose)
n: degere o ka hydroxypropylation (pūʻulu hydroxypropyl no ka ʻāpana glucose)
x: ka helu o nā ʻāpana glucose i ke kaulahao cellulose
Nā hiʻohiʻona a me nā noi:
Solubility: Hiki ke hoʻoheheʻe ʻia ka HPMC i ka wai, a ʻo ke degere o ka hoʻololi ʻana e pili ana i kona ʻano solubility.Hoʻokumu ʻo ia i kahi hāʻina maʻemaʻe a viscous i loko o ka wai, kūpono ia no nā ʻano hana like ʻole.
Viscosity: ʻO ka viscosity o ka hopena HPMC e pili ana i nā mea e like me ke kaumaha molekala a me ke kiʻekiʻe o ka hoʻololi.He mea koʻikoʻi kēia waiwai no nā noi e like me nā lāʻau lapaʻau e koi ana i nā hoʻopuka hoʻokuʻu ʻia.
Hoʻokumu kiʻiʻoniʻoni: Hiki i ka HPMC ke hana i nā kiʻiʻoniʻoni lahilahi i ka maloʻo ʻana o ka hopena, e hoʻohana pono ai i nā uhi i ka lāʻau lapaʻau, meaʻai a me nā ʻoihana ʻē aʻe.
Stabilizers and Thickeners: Ma ka ʻoihana meaʻai, hoʻohana ʻia ʻo HPMC ma ke ʻano he mānoanoa a me ka stabilizer i nā ʻano huahana like ʻole, me nā mea ʻono, nā mea ʻono, a me nā meaʻai bakena.
Hoʻohana Lapaʻau Lapaʻau: Hoʻohana nui ʻia ʻo HPMC i nā ʻano hana lāʻau lapaʻau, me nā papa, nā capsules, a me nā hoʻonā ophthalmic, ma muli o kāna mau waiwai hoʻokuʻu ʻia a me ka biocompatibility.
Ka hana a me ka uhi: Hoʻohana ʻia ʻo HPMC i nā mea hana e like me nā morta, nā ʻāpana tile a me nā plasters.Hoʻohana ʻia ia ma ke ʻano he mānoanoa a me ka stabilizer i ka pena a me ka hoʻopili ʻana.
Nā huahana mālama pilikino: Ma ka ʻoihana hoʻonaninani a me ka ʻoihana mālama pilikino, loaʻa ʻo HPMC i nā huahana e like me ka creams, lotions a me nā shampoos, kahi e hāʻawi ai i ke ʻano a me ke kūpaʻa.
Loaʻa ka Hydroxypropyl methylcellulose e ka methylation a me ka hydroxypropylation o cellulose.He polymer multi-purpose me ka nui o ka hoʻohana.ʻO kāna mau waiwai kūʻokoʻa he mea waiwai ia i nā ʻoihana e like me ka lāʻau lapaʻau, ka meaʻai, ke kūkulu ʻana a me ka mālama pilikino.Hiki i ka hoʻololi ʻana i ka cellulose ke hoʻoponopono maikaʻi i nā waiwai o HPMC, e lilo ia i mea koʻikoʻi o nā huahana he nui a mākou e hālāwai ai i ko mākou ola i kēlā me kēia lā.
Ka manawa hoʻouna: Jan-10-2024